منابع مشابه
Truncated forms of RUNX3 unlike full length protein alter cell proliferation in a TGF-β context dependent manner
The Runt related transcription factors (RUNX) are recognized as key players in suppressing or promoting tumor growth. RUNX3, a member of this family, is known as a tumor suppressor in many types of cancers, although such a paradigm was challenged by some researchers. The TGF-β pathway governs major upstream signals to activate RUNX3. RUNX3 protein consists of several regions and domains. The Ru...
متن کاملTruncated forms of RUNX3 unlike full length protein alter cell proliferation in a TGF-β context dependent manner
The Runt related transcription factors (RUNX) are recognized as key players in suppressing or promoting tumor growth. RUNX3, a member of this family, is known as a tumor suppressor in many types of cancers, although such a paradigm was challenged by some researchers. The TGF-β pathway governs major upstream signals to activate RUNX3. RUNX3 protein consists of several regions and domains. The Ru...
متن کاملSimpler Context-Dependent Logical Forms via Model Projections
We consider the task of learning a contextdependent mapping from utterances to denotations. With only denotations at training time, we must search over a combinatorially large space of logical forms, which is even larger with context-dependent utterances. To cope with this challenge, we perform successive projections of the full model onto simpler models that operate over equivalence classes of...
متن کاملContext-dependent regulatory mechanism of the splicing factor hnRNP L.
Splicing regulatory proteins often have distinct activities when bound to exons versus introns. However, less clear is whether variables aside from location can influence activity. HnRNP L binds to a motif present in both CD45 variable exons 4 and 5 to affect their coordinate repression. Here, we show that, in contrast to its direct repression of exon 4, hnRNP L represses exon 5 by countering t...
متن کاملResource Allocation through Context-dependent data envelopment analysis
System designs, optimizing resource allocation to organization units, is still being considered as a complicated problem especially when there are multiple inputs and outputs related to a unit. The algorithm presented here will divide the frontiers obtained with DEA. In this way, we investigate a new approach for resource allocation.
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ژورنال
عنوان ژورنال: Information and Control
سال: 1979
ISSN: 0019-9958
DOI: 10.1016/s0019-9958(79)90199-2